We are now many weeks into an international lockdown caused by the coronavirus pandemic. This situation has introduced us to a whole new vocabulary and given us a whole new level of respect for frontline workers. A friend of mine, Ewan Goligher, is a doctor and scientist who has dedicated his career to the intricacies of mechanical ventilation (specifically, characterizing the mechanisms and impact of injury to the lung and diaphragm during mechanical ventilation). He was willing to take a bit of time to answer a few of the questions I’ve had about COVID-19, about the importance of ventilators, and a few other related topics. I hope you find it as enlightening as I did!

When we’ve talked in the past you’ve told me a little bit about your background as an expert in mechanical ventilation. I probably mostly tried to change the subject, but here in the midst of a pandemic caused by a respiratory disease, suddenly I’m riveted. So thanks for the opportunity to chat. Acknowledging that I’ve got basically no knowledge of virology, biology, or other key fields, what should someone like me know about this virus and the disease it causes?

The coronavirus (properly


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